• This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. A pseudogene of this gene have been defined on chromosome 6. Alternative splicing results in multiple transcript variants [provided by RefSeq, May 2014]
  

WASF3 (WASP Family Member 3) is a Protein Coding gene. Diseases associated with WASF3 include Wiskott-Aldrich Syndrome and Ganglioneuroblastoma. Among its related pathways are Regulation of actin dynamics for phagocytic cup formation and Signaling by Rho GTPases. Gene Ontology (GO) annotations related to this gene include actin binding. An important paralog of this gene is WASF1.